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Yong-Bin Yan Selected Research

Lanosterol

10/2021Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells.
12/2018Lanosterol and 25-hydroxycholesterol dissociate crystallin aggregates isolated from cataractous human lens via different mechanisms.
10/2018Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
10/2015Corrigendum: Lanosterol reverses protein aggregation in cataracts.
7/2015Lanosterol reverses protein aggregation in cataracts.

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Yong-Bin Yan Research Topics

Disease

23Cataract (Cataracts)
10/2021 - 04/2010
5Blindness (Hysterical Blindness)
12/2018 - 02/2013
4Neoplasms (Cancer)
02/2021 - 05/2013
2Cataract microcornea syndrome
01/2016 - 03/2011
2Shock
04/2015 - 01/2012
2Dehydration (Water Stress)
01/2008 - 02/2006
1Genomic Instability
01/2021
1Stomach Neoplasms (Stomach Cancer)
02/2015
1Ovarian Neoplasms (Ovarian Cancer)
05/2013

Drug/Important Bio-Agent (IBA)

18Crystallins (Crystallin)IBA
03/2021 - 04/2010
13Proteins (Proteins, Gene)FDA Link
10/2021 - 01/2008
5LanosterolIBA
10/2021 - 07/2015
2Pharmaceutical PreparationsIBA
10/2021 - 12/2018
2RNA (Ribonucleic Acid)IBA
02/2021 - 01/2021
2Tryptophan (L-Tryptophan)FDA Link
10/2018 - 01/2011
2Creatine Kinase (Creatine Phosphokinase)IBA
01/2016 - 05/2013
2SaltsIBA
04/2015 - 01/2012
2Codon (Codons)IBA
02/2012 - 01/2011
1MicroRNAs (MicroRNA)IBA
01/2021
125-hydroxycholesterolIBA
12/2018
1TriterpenesIBA
10/2018
1Guanidine (Guanidine Nitrate)FDA Link
10/2017
1Biomarkers (Surrogate Marker)IBA
01/2016
1poly(A)-specific ribonucleaseIBA
02/2015
1Protein AggregatesIBA
05/2014
1AcidsIBA
05/2014
1Protein Isoforms (Isoforms)IBA
05/2013
1Peptide Hydrolases (Proteases)FDA Link
02/2013
1Glycine (Aminoacetic Acid)FDA LinkGeneric
02/2012
1Cysteine (L-Cysteine)FDA Link
02/2012
1Arginine (L-Arginine)FDA Link
01/2011
1AmidesIBA
01/2008
1Peptides (Polypeptides)IBA
01/2008
1Lysine (L-Lysine)FDA Link
01/2008
1Pancreatic Ribonuclease (Ribonuclease A)IBA
01/2008
1ElementsIBA
02/2006

Therapy/Procedure

2Lenses
10/2021 - 07/2015
1Transcutaneous Electric Nerve Stimulation (TENS)
07/2015
1Therapeutics
05/2013